A comprehensive review published in Frontiers in Oncology explores the intricate connections between gut, breast, and oral microbiomes in breast cancer development and progression. Analyzing data from 33 studies, researchers found distinct microbial patterns and reduced diversity in breast cancer patients compared to healthy individuals. Notably, microbial imbalances were linked to specific cancer subtypes and treatment outcomes.
The study highlights the potential of microbiomes as biomarkers for diagnosis, prognosis, and personalized treatment strategies, emphasizing their influence on the immune system and cancer therapy responsiveness. These findings pave the way for advanced research into microbiome-based interventions in breast cancer care.