A new study explores the use of cannabis oil to alleviate chemotherapy-related side effects in breast cancer patients. Conducted at King Chulalongkorn Memorial Hospital, the trial involves 90 participants and investigates the efficacy of cannabis oil in improving quality of life, symptom distress, and pain levels. Additionally, the research examines microbial alterations, cytokine levels, and pharmacogenetic profiles pre- and post-treatment. Participants will receive Ganja Oil, Metta Osot, or a placebo over 12 weeks, with assessments spanning quality of life, microbial diversity, and adverse reactions. The study aims to provide evidence for integrating cannabis oil into breast cancer care practices.