Announcement/Events


Congratulations to Dr.Gang Chen on his latest publication in Nature Communications.

Congratulations to Dr.Gang Chen, our new Adjunct Professor at Graduate Affairs, Faculty of Medicine, Chulalongkorn University, on his latest publication in Nature Communications.
**Research News Summary: XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias**
Scientists have introduced a game-changing method called Cross-Population Fine-Mapping (XMAP) to address key challenges in understanding complex traits identified by genome-wide association studies (GWASs). XMAP leverages genetic diversity to overcome issues like strong linkage disequilibrium among variants, computational inefficiency, and hidden confounding bias in GWAS data. It achieves greater statistical power, improved control of false positives, and higher computational efficiency compared to existing methods. Notably, XMAP can be integrated with single-cell datasets, enhancing the interpretation of causal variants at single-cell resolution. This breakthrough promises a deeper understanding of complex traits and diseases.
Cai, M., Wang, Z., Xiao, J. et al. XMAP: Cross-population fine-mapping by leveraging genetic diversity and accounting for confounding bias. Nat Commun 14, 6870 (2023).

v